Cardiovascular: cardiac irregularities, hypotension, orthostatic effects including orthostatic hypotension, hypertension, syncope, phlebitis, palpitation. However, patients with markedly irregular on-off responses to levodopa have not been shown to benefit from SINEMET. False-negative tests may result with the use of glucose-oxidase methods of testing for glucosuria. In such patients, cardiac function should be monitored with particular care during the period of initial dosage adjustment, in facility with provisions for intensive cardiac care. In considering whether to give LODOSYN with SINEMET Carbidopa-Levodopa or with levodopa to patients who have nausea and or vomiting, the physician should be aware that, while many patients may be expected to carbidopa cheap free improve, some may not. It is not known whether carbidopa will be harmful to an unborn baby.